Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753722 | 0.83 | APP (0.32) | APPKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8606962 | 0.83 | KDM6B (0.35) | EGLN1APPKDM4ENPC1ALDH1A1 | |
| SCHEMBL8605684 | 0.81 | PGK1 (0.32) | KDM4EALDH1A1RAB9A | |
| SCHEMBL8608922 | 0.78 | ALDH1A1 (0.33) | KDM4ENPC1ALDH1A1POLBGAA | |
| SCHEMBL8606803 | 0.77 | CPB2 (0.36) | KDM4ENPC1ALDH1A1POLBGAA | |
| SCHEMBL8607307 | 0.76 | APP (0.34) | APPKDM4ENPC1ALDH1A1POLB | |
| SCHEMBL9753486 | 0.76 | APP (0.35) | APP | |
| SCHEMBL8607292 | 0.75 | MAP3K5 (0.32) | EGLN1 | |
| SCHEMBL9753460 | 0.75 | APP (0.32) | APPKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL9753680 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436831-A2 | Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | disclosed |