Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934604 | 0.85 | RAB9A (0.62) | RAB9AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9621679 | 0.77 | RAB9A (1.00) | RAB9AMEN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL21382353 | 0.74 | RAB9A (0.64) | RAB9AMEN1KMT2ACSNK2A2CSNK2B | |
| SCHEMBL13409103 | 0.74 | RAB9A (0.64) | RAB9AMEN1KMT2AALDH1A1CSNK2A2 | |
| SCHEMBL27591329 | 0.74 | L3MBTL1 (0.72) | RAB9AKMT2AL3MBTL1LMNAMAPT | |
| SCHEMBL3932546 | 0.73 | RAB9A (0.62) | RAB9AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3932557 | 0.73 | RAB9A (0.62) | RAB9AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4875352 | 0.73 | RAB9A (0.62) | RAB9AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9845157 | 0.72 | RAB9A (0.61) | RAB9AMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9047133 | 0.71 | RAB9A (0.60) | RAB9AMEN1KMT2AALDH1A1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412404-A2 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |