Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083523 | 0.79 | RAB9A (0.59) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL9621679 | 0.76 | RAB9A (1.00) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL13409103 | 0.73 | RAB9A (0.64) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL21382353 | 0.73 | RAB9A (0.64) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL8934604 | 0.72 | RAB9A (0.62) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL3932546 | 0.72 | RAB9A (0.62) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL9845155 | 0.72 | RAB9A (0.62) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL3932557 | 0.72 | RAB9A (0.62) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL4875352 | 0.72 | RAB9A (0.62) | RAB9AMEN1KMT2ALMNACSNK2A2 | |
| SCHEMBL3931075 | 0.71 | AOC3 (0.64) | RAB9AMEN1KMT2ACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412404-A2 | Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |