Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080473 | 0.83 | NPC1 (0.43) | RAB9ALMNAMEN1KMT2AMAPT | |
| SCHEMBL9845157 | 0.79 | RAB9A (0.61) | RAB9ALMNAMEN1KMT2ACSNK2A2 | |
| SCHEMBL6799338 | 0.76 | RAB9A (0.70) | RAB9ALMNAMEN1KMT2AMAPT | |
| SCHEMBL4295980 | 0.75 | L3MBTL1 (0.51) | RAB9ALMNAMEN1KMT2AMAPT | |
| SCHEMBL9621679 | 0.74 | RAB9A (1.00) | RAB9ALMNAMEN1KMT2ACSNK2A2 | |
| SCHEMBL7083520 | 0.74 | MAPT (0.58) | RAB9ALMNAMEN1KMT2ACSNK2A2 | |
| SCHEMBL21382353 | 0.74 | RAB9A (0.64) | RAB9ALMNAMEN1KMT2ACSNK2A2 | |
| SCHEMBL13409103 | 0.71 | RAB9A (0.64) | RAB9ALMNAMEN1KMT2ACSNK2A2 | |
| SCHEMBL12190585 | 0.71 | L3MBTL1 (0.57) | RAB9ALMNAKMT2ACSNK2A2CSNK2B | |
| SCHEMBL8934604 | 0.71 | RAB9A (0.62) | RAB9ALMNAMEN1KMT2ACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |