Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.51 |
| ▸ | PTGIR | P43119 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845261 | 1.00 | TBXAS1 (0.51) | TBXAS1PTGIRPTGS1PTGS2TSHR | |
| SCHEMBL5514714 | 1.00 | TBXAS1 (0.51) | TBXAS1PTGIRPTGS1PTGS2TSHR | |
| Water SCHEMBL9845268 | 0.98 | TBXAS1 (0.50) | TBXAS1PTGIRPTGS1PTGS2TSHR | |
| SCHEMBL5521617 | 0.98 | TBXAS1 (0.49) | TBXAS1PTGIRPTGS1PTGS2TSHR | |
| SCHEMBL3489062 | 0.93 | TBXAS1 (0.42) | TBXAS1PTGIRTSHRLMNAFABP4 | |
| SCHEMBL4663218 | 0.85 | EGLN3 (0.50) | TSHRLMNAESR1KMT2A | |
| SCHEMBL6446995 | 0.84 | LMNA (0.40) | LMNATDP1ALOX15KMT2A | |
| Hydrochloric Acid SCHEMBL17337686 | 0.83 | EGLN3 (0.48) | TSHRLMNAESR1KMT2A | |
| SCHEMBL12863692 | 0.82 | THRB (0.42) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL7100687 | 0.80 | DAO (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417449-A1 | Arylpyrazole derivatives as platelet aggregation inhibitors | Bristol-Myers Squibb Company (US) | 1991-03-20 | — | — | EP | disclosed |