Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2047123 | 0.80 | CYP2C19 (0.47) | MAOAMAOBCYP2C19HIF1AALDH1A1 | |
| SCHEMBL14921 | 0.79 | TAAR1 (0.48) | MAOAMAOBCYP2C19HIF1AALDH1A1 | |
| SCHEMBL296800 | 0.77 | MAOA (0.42) | MAOAMAOBCYP2C19HIF1AALDH1A1 | |
| SCHEMBL5033208 | 0.77 | MAOA (0.42) | MAOAMAOBCYP2C19HIF1AATM | |
| SCHEMBL2170468 | 0.75 | KCNN4 (0.48) | CYP2C19HIF1AKCNN4ALDH1A1 | |
| SCHEMBL28810886 | 0.75 | CYP2C19 (0.59) | CYP2C19HIF1AKCNN4ALDH1A1MAPT | |
| SCHEMBL9845388 | 0.75 | CYP2C19 (0.39) | CYP2C19HIF1AKCNN4ALDH1A1 | |
| Carbon Tetrachloride SCHEMBL28327161 | 0.74 | TAAR1 (0.44) | MAOAMAOBCYP2C19HIF1AALDH1A1 | |
| SCHEMBL2399414 | 0.74 | MAOA (0.47) | MAOAMAOBCYP2C19HIF1AALDH1A1 | |
| SCHEMBL23287920 | 0.73 | MAOA (0.42) | MAOAMAOBCYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1459726-B1 | ADHESIVES FOR DENTAL USE | TOKUYAMA CORP (JP) | 2013-10-02 | — | — | EP | disclosed |
| US-20100120941-A1 | ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT | TOKUYAMA DENTAL CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2127631-A1 | ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT | Tokuyama Dental Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-7041714-B2 | Dental adhesive | TOKUYAMA CORPORATION (JP) | 2006-05-09 | — | — | US | disclosed |
| EP-1459726-A1 | ADHESIVES FOR DENTAL USE | TOKUYAMA CORPORATION (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040077746-A1 | Adhesives for dental use | TOKUYAMA CORPORATION (JP) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077746-A1 | Adhesives for dental use | ICAM1, CDH1, VCAM1 | MAOA 2282/4885MAOB 3635/4885CYP2C19 2534/4885 |
| US-20100120941-A1 | ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT | ICAM1, ITGB8, TRA2B | MAOA 3212/4885MAOB 3201/4885CYP2C19 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.