Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.55 |
| ▸ | NNMT | P40261 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845369 | 0.91 | LCK (0.54) | HCAR3NNMTSMN1; SMN2LCKFYN | |
| SCHEMBL9845322 | 0.83 | HDAC1 (0.60) | S1PR4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4064646 | 0.81 | KMT2A (0.64) | S1PR4MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL259362 | 0.79 | MEN1 (0.73) | HCAR3MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9845375 | 0.78 | RXFP1 (0.48) | S1PR4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18715411 | 0.77 | HCAR3 (0.70) | HCAR3NNMTMAPTSMN1; SMN2 | |
| SCHEMBL9523578 | 0.76 | S1PR4 (0.55) | S1PR4MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4253868 | 0.75 | P4HTM (0.67) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9845318 | 0.74 | LCK (0.57) | KMT2ALCKFYNSRC | |
| SCHEMBL9523014 | 0.74 | S1PR4 (0.69) | S1PR4MAPTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405931-A2 | Improvements in and relating to anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4973597-A | PYRIDINECARBOXAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1990-11-27 | — | — | US | disclosed |