Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522743 | 0.87 | S1PR4 (0.58) | S1PR4NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4138460 | 0.86 | POLB (0.67) | S1PR4NPC1RAB9AKDM4EMAPT | |
| SCHEMBL15775319 | 0.85 | KDM4E (0.59) | S1PR4NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1815922 | 0.85 | KDM4E (0.77) | S1PR4NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL11123393 | 0.85 | RXFP1 (0.59) | S1PR4NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9522953 | 0.85 | S1PR4 (0.56) | S1PR4NPC1RAB9AKDM4EALDH1A1 | |
| Ameltolide SCHEMBL635392 | 0.85 | S1PR4 (0.56) | S1PR4KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2307872 | 0.85 | S1PR4 (0.56) | S1PR4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9523578 | 0.84 | S1PR4 (0.55) | S1PR4NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7301820 | 0.84 | SMN1; SMN2 (0.61) | S1PR4NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279633-B1 | ANTICONVULSANT AGENTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4981866-A | BENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4939163-A | 4-substituted benzamide derivatives | ELI LILLY AND COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4835181-A | Anticonvulsant agents using cyano dimethylphenyl benzamides | ELI LILLY AND COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0279633-A2 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |