Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.70 |
| ▸ | NNMT | P40261 | 1/20 | 0.68 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487358 | 0.85 | NNMT (0.54) | HCAR3NNMTBAZ2BGRM5HDAC6 | |
| SCHEMBL29424855 | 0.85 | NNMT (0.54) | HCAR3NNMTBAZ2BGRM5HDAC6 | |
| SCHEMBL19736133 | 0.84 | PTK2 (0.57) | HCAR3NNMTBAZ2BGRM5TSHR | |
| SCHEMBL12588541 | 0.82 | HCAR3 (0.72) | HCAR3NNMTMAPT | |
| SCHEMBL30403146 | 0.82 | HCAR3 (1.00) | HCAR3NNMT | |
| SCHEMBL185895 | 0.82 | HCAR3 (1.00) | HCAR3NNMT | |
| SCHEMBL12678701 | 0.81 | HCAR3 (0.69) | HCAR3NNMTBAZ2BGRM5HPGD | |
| SCHEMBL9889744 | 0.81 | BAZ2B (0.49) | HCAR3NNMTBAZ2BGRM5HDAC6 | |
| SCHEMBL4320704 | 0.81 | NNMT (1.00) | HCAR3NNMTSMN1; SMN2APP | |
| Hydrochloric Acid SCHEMBL4035906 | 0.81 | HCAR3 (0.96) | HCAR3NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230194537-A1 | COMPOUNDS FOR THE DETECTION OF GLYCANS | Life Technologies Corporation | 2023-06-22 | — | — | US | disclosed |
| EP-2764406-B1 | COMPOSITIONS AND METHODS FOR TUMOR IMAGING AND TARGETING BY A CLASS OF ORGANIC HEPTAMETHINE CYANINE DYES THAT POSSESS DUAL NUCLEAR AND NEAR-INFRARED PROPERTIES | CEDARS SINAI MEDICAL CENTER (US) | 2018-03-14 | — | — | EP | disclosed |
| US-9610370-B2 | Compositions and methods for tumor imaging and targeting by a class of organic heptamethine cyanine dyes that possess dual nuclear and near-infrared properties | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2017-04-04 | — | — | US | disclosed |