Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845679 | 1.00 | KDM1A (0.42) | KDM1ASNCAEGFRABL1ABL2 | |
| SCHEMBL9845688 | 0.80 | TP53 (0.45) | EGFRABL1ABL2ESR1ESR2 | |
| SCHEMBL9845691 | 0.80 | TP53 (0.45) | EGFRABL1ABL2ESR1ESR2 | |
| SCHEMBL9255530 | 0.79 | PTGS2 (0.54) | KDM1ASNCAESR1ESR2TUBB1 | |
| SCHEMBL9255534 | 0.79 | PTGS2 (0.54) | KDM1ASNCAESR1ESR2TUBB1 | |
| SCHEMBL2085781 | 0.78 | AKR1C3 (0.52) | KDM1ASNCAEGFRABL1ABL2 | |
| SCHEMBL2085780 | 0.78 | AKR1C3 (0.52) | KDM1ASNCAEGFRABL1ABL2 | |
| SCHEMBL7631589 | 0.76 | MAPT (0.66) | KDM1ASNCAEGFRABL1TRPA1 | |
| SCHEMBL11599639 | 0.73 | CNR2 (0.64) | KDM1ASNCAMAPTMCL1TUBB1 | |
| SCHEMBL3225328 | 0.72 | TRPA1 (0.52) | KDM1ASNCATRPA1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100405220-C | Acid-decomposable resin composition containing ketone-aldehyde copolymer | NIPPON SODA CO (JP) | 2008-07-23 | — | — | CN | disclosed |
| CN-1630835-A | Acid-decomposable resin composition containing ketone-aldehyde copolymer | NIPPON SODA CO (JP) | 2005-06-22 | — | — | CN | disclosed |
| EP-0410379-A2 | Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-01-30 | — | — | EP | disclosed |