SCHEMBL9845807

SCHEMBL9845807

O=C(O)c1cc(O)c(O)c(O)c1C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.52
THRB P10828 1/20 0.50
KDM4E B2RXH2 3/20 0.49
KMT2A Q03164 2/20 0.49
CYP2C8 P10632 1/20 0.49
CYP2C9 P11712 1/20 0.49
MEN1 O00255 1/20 0.49
USP2 O75604 1/20 0.49
GAA P10253 1/20 0.49
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
ALDH1A1 P00352 3/20 0.46
BCL2L1 Q07817 1/20 0.46
HPGD P15428 3/20 0.46
LMNA P02545 2/20 0.46
PKM P14618 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
RECQL P46063 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7105629 0.85 KDM4E (0.56) THRBKDM4EKMT2AMEN1GAA
SCHEMBL7896024 0.82 ALDH1A1 (0.52) KMT2ACYP2C8CYP2C9MEN1USP2
SCHEMBL29727844 0.82 ALDH1A1 (0.52) KMT2ACYP2C8CYP2C9MEN1USP2
SCHEMBL3714635 0.81 AKR1C3 (0.57) AKR1C3THRBKDM4EKMT2ACYP2C8
SCHEMBL245255 0.81 BCL2 (0.62) AKR1C3KDM4EKMT2ACYP2C8CYP2C9
SCHEMBL27538497 0.81 MAPT (0.50) AKR1C3THRBKDM4EKMT2ACYP2C8
SCHEMBL1650146 0.80 AKR1C3 (0.60) AKR1C3KDM4EKMT2ACYP2C8CYP2C9
SCHEMBL6903701 0.80 SELL (0.48) AKR1C3THRBKDM4EKMT2ACYP2C9
Salicylic Acid SCHEMBL28119337 0.80 KDM4E (0.58) AKR1C3THRBKDM4EKMT2ACYP2C8
SCHEMBL8399976 0.79 GAA (0.55) AKR1C3KDM4EKMT2ACYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP claimed
CN-1288497-C Photo sensitive composition and negative lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2006-12-06 CN disclosed
CN-1388412-A Photo sensitive composition and negative lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2003-01-01 CN disclosed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP disclosed