Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | LIG1 | P18858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245255 | 0.90 | BCL2 (0.62) | KDM4EHPGDALDH1A1AKR1C3BCL2 | |
| Benzophenone SCHEMBL28941308 | 0.88 | BCL2 (0.60) | KDM4EHPGDALDH1A1AKR1C3BCL2 | |
| SCHEMBL29106579 | 0.88 | BCL2 (0.60) | KDM4EHPGDALDH1A1AKR1C3BCL2 | |
| Phloroglucinol SCHEMBL9310647 | 0.85 | BCL2 (0.57) | KDM4EHPGDALDH1A1AKR1C3BCL2 | |
| SCHEMBL28086265 | 0.84 | ACMSD (0.67) | KDM4EHPGDALDH1A1AKR1C3BCL2 | |
| Phenyl Salicylate SCHEMBL28284410 | 0.83 | HPGD (0.65) | KDM4EHPGDALDH1A1SMN1; SMN2BCL2 | |
| SCHEMBL1952546 | 0.83 | GSTA1 (0.55) | KDM4EHPGDCA12ALDH1A1CA1 | |
| SCHEMBL29493125 | 0.83 | GSTA1 (0.55) | KDM4EHPGDCA12ALDH1A1CA1 | |
| Benzophenone SCHEMBL8149577 | 0.82 | ALDH1A1 (0.78) | KDM4EHPGDCA12ALDH1A1CA1 | |
| Phthalic Acid SCHEMBL11577907 | 0.81 | AKR1C3 (0.76) | KDM4EHPGDCA12ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103874731-B | Epoxy formulations and methods for producing relief patterns on low surface energy substrates | 微量化学公司 | 2017-02-15 | — | — | CN | disclosed |