Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TNF | P01375 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845812 | 0.84 | KMT2A (0.47) | NPSR1LMNAMAPTHSD17B10USP2 | |
| SCHEMBL9850703 | 0.82 | ALDH1A1 (0.46) | NPSR1LMNAMAPTUSP2MAPK1 | |
| SCHEMBL9845852 | 0.79 | NPSR1 (0.41) | NPSR1LMNAMAPTUSP2MAPK1 | |
| SCHEMBL9850726 | 0.79 | NPSR1 (0.50) | NPSR1LMNAMAPTHSD17B10USP2 | |
| SCHEMBL4095906 | 0.78 | ALDH1A1 (0.39) | NPSR1LMNAMAPTHSD17B10USP2 | |
| SCHEMBL5795312 | 0.76 | MAPT (0.49) | NPSR1LMNATNFMAPTHSD17B10 | |
| SCHEMBL4331304 | 0.74 | NPSR1 (0.51) | NPSR1LMNATNFMAPTUSP2 | |
| SCHEMBL5811305 | 0.74 | GAA (0.63) | NPSR1TNFMAPTHSD17B10MAPK1 | |
| SCHEMBL6990864 | 0.70 | NPSR1 (0.41) | NPSR1LMNATNFMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6988094 | 0.69 | NPSR1 (0.40) | NPSR1LMNATNFMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445467-A1 | Renin inhibitors and antiviral agents | Beecham Group p.l.c. (GB) | 1991-09-11 | — | — | EP | disclosed |