Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850726 | 0.92 | NPSR1 (0.50) | KMT2AMEN1GAACHRM1NPSR1 | |
| SCHEMBL9845834 | 0.84 | NPSR1 (0.53) | GAANPSR1MAPTALDH1A1MAPK1 | |
| SCHEMBL4095906 | 0.83 | ALDH1A1 (0.39) | KMT2AMEN1GAACHRM1NPSR1 | |
| SCHEMBL9850703 | 0.81 | ALDH1A1 (0.46) | KMT2AMEN1NPSR1MAPTALDH1A1 | |
| SCHEMBL9850715 | 0.80 | NPSR1 (0.48) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL9845852 | 0.78 | NPSR1 (0.41) | KMT2AMEN1NPSR1MAPTKDM4E | |
| SCHEMBL7269755 | 0.73 | MEN1 (0.63) | KMT2AMEN1CHRM1NPSR1MAPT | |
| SCHEMBL19456927 | 0.72 | MEN1 (0.62) | KMT2AMEN1GAANPSR1MAPT | |
| SCHEMBL3085058 | 0.69 | KMT2A (0.88) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL30808610 | 0.69 | KMO (0.58) | KMT2AMEN1NPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445467-A1 | Renin inhibitors and antiviral agents | Beecham Group p.l.c. (GB) | 1991-09-11 | — | — | EP | disclosed |