SCHEMBL9845872

SCHEMBL9845872

CC(O)Oc1ccc(CC(C)c2ccc(OC(C)O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.58
ESR2 Q92731 1/20 0.58
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
FFAR1 O14842 1/20 0.40
POLB P06746 1/20 0.40
SLC6A4 P31645 1/20 0.39
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
PTGS2 P35354 4/20 0.37
PTGS1 P23219 3/20 0.37
LMNA P02545 2/20 0.37
CYP2C9 P11712 2/20 0.37
AKR1C3 P42330 2/20 0.37
CXCR1 P25024 2/20 0.37
CXCR2 P25025 2/20 0.37
TSHR P16473 2/20 0.37
ALB P02768 1/20 0.37
ALOX5 P09917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30385102 0.82 ESR1 (0.50) ESR1ESR2CYP1A2CYP2D6CYP2C19
SCHEMBL17679434 0.81 ALDH1A1 (0.54) CYP2C9TSHRALDH1A1
SCHEMBL10203858 0.81 ALDH1A1 (0.54) CYP2C9TSHRALDH1A1
SCHEMBL10493597 0.79 LMNA (0.55) ESR1ESR2CYP1A2LMNATSHR
SCHEMBL10338355 0.79 CYP1A2 (0.63) ESR1ESR2CYP1A2CYP2D6CYP2C19
SCHEMBL10596769 0.78 ESR1 (0.50) ESR1ESR2PPARGPPARATSHR
SCHEMBL5433337 0.78 LTA4H (0.47) ESR1ESR2CYP1A2CYP2D6CYP2C19
SCHEMBL10977168 0.77 PARP10 (0.48) CYP1A2CYP2D6CYP2C19POLBLMNA
SCHEMBL17961880 0.77 PARP10 (0.48) CYP1A2CYP2D6CYP2C19POLBLMNA
SCHEMBL97898 0.77 PARP10 (0.48) CYP1A2CYP2D6CYP2C19POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415728-A2 Process for preparing blow molded articles MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-03-06 EP disclosed
US-4417011-A UNSATURATED POLYESTER MITSUI TOATSU CHEMICALS, INC. (JP) 1983-11-22 US disclosed