Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761347 | 0.93 | GNAO1 (0.41) | SIGMAR1GNAO1GNAI3GNAI1OPRM1 | |
| SCHEMBL10386726 | 0.89 | SMN1; SMN2 (0.39) | SIGMAR1SMN1; SMN2GNAO1GNAI3GNAI1 | |
| SCHEMBL7428169 | 0.84 | SMN1; SMN2 (0.39) | SIGMAR1SMN1; SMN2OPRM1CXCR4CHRM5 | |
| SCHEMBL991697 | 0.80 | SMN1; SMN2 (0.44) | SIGMAR1SMN1; SMN2CHRM2SLC6A2SLC6A4 | |
| SCHEMBL22248563 | 0.79 | SMN1; SMN2 (0.36) | SIGMAR1SMN1; SMN2CXCR4CHRM5CHRM3 | |
| SCHEMBL2945288 | 0.79 | SMN1; SMN2 (0.36) | SIGMAR1SMN1; SMN2CXCR4CHRM5CHRM3 | |
| SCHEMBL9420793 | 0.78 | SMN1; SMN2 (0.33) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL14096698 | 0.78 | SMN1; SMN2 (0.51) | SIGMAR1SMN1; SMN2GNAO1GNAI3GNAI1 | |
| SCHEMBL15284195 | 0.78 | CHRM2 (0.50) | SIGMAR1SMN1; SMN2GNAO1GNAI3GNAI1 | |
| SCHEMBL9420761 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2CHRM2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423577-A1 | Polyamidelastomers, their preparation and use | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |