SCHEMBL9845965

SCHEMBL9845965

NCCOc1ccc2ncsc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.45
TDP1 Q9NUW8 3/20 0.44
PKM P14618 2/20 0.44
TAAR1 Q96RJ0 1/20 0.44
DYRK1A Q13627 1/20 0.44
LTA4H P09960 2/20 0.43
PLA2G2A P14555 1/20 0.43
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HKDC1 Q2TB90 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 4/20 0.42
FGFR1 P11362 1/20 0.40
HSD17B10 Q99714 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMYD3 Q9H7B4 1/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17861608 0.83 DRD2 (0.45) DRD2TDP1PKMDYRK1ANPC1
SCHEMBL23366727 0.83 ALDH1A1 (0.48) DRD2TDP1PKMDYRK1ALTA4H
SCHEMBL9178965 0.83 PKM (0.48) DRD2TDP1PKMLTA4HNPC1
SCHEMBL27354687 0.82 DRD2 (0.44) DRD2TDP1PKMDYRK1ANPC1
SCHEMBL17848540 0.81 NPC1 (0.47) DRD2TDP1PKMDYRK1ANPC1
SCHEMBL10610945 0.81 NR5A1 (0.47) DRD2TDP1PKMLTA4HNPC1
SCHEMBL10572843 0.80 GAA (0.45) DRD2TDP1PKMDYRK1ANPC1
SCHEMBL4160781 0.79 ALDH1A1 (0.60) DRD2TDP1PKMNPC1RAB9A
SCHEMBL27890720 0.75 SMN1; SMN2 (0.43) DRD2TDP1PKMDYRK1ANPC1
SCHEMBL13167862 0.75 ALDH1A1 (0.50) DRD2TDP1PKMDYRK1ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427963-A1 Process for the preparation of pure asymmetric disubstituted urea AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) 1991-05-22 EP disclosed
US-4257942-A New water-insoluble azo dyes AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) 1981-03-24 US disclosed