Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309290 | 0.91 | PPARG (0.46) | PPARGACHEAGTR1 | |
| SCHEMBL9308844 | 0.88 | PPARG (0.45) | PPARGACHEAGTR1 | |
| SCHEMBL9308911 | 0.87 | PPARG (0.41) | PPARGACHEHPGDKDM4ENPSR1 | |
| SCHEMBL9846018 | 0.87 | ACHE (0.44) | PPARGACHEAGTR1 | |
| SCHEMBL9846004 | 0.86 | PPARG (0.44) | PPARGACHEAGTR1 | |
| SCHEMBL9846045 | 0.86 | ACHE (0.43) | PPARGACHEHPGDAGTR1 | |
| SCHEMBL9846006 | 0.86 | PPARG (0.42) | PPARGACHEAGTR1 | |
| SCHEMBL9846082 | 0.85 | ACHE (0.42) | PPARGACHEAGTR1 | |
| SCHEMBL1894428 | 0.84 | PPARG (0.50) | PPARGACHEAGTR1 | |
| SCHEMBL9846003 | 0.83 | PPARG (0.40) | PPARGACHEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |