Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308565 | 0.94 | PPARG (0.45) | PPARGAGTR1 | |
| SCHEMBL9309739 | 0.90 | PPARG (0.39) | PPARGACHEALDH1A1HPGDKDM4E | |
| SCHEMBL9846031 | 0.87 | PPARG (0.43) | PPARGACHEAGTR1HPGDKDM4E | |
| SCHEMBL9309290 | 0.86 | PPARG (0.46) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9846004 | 0.85 | PPARG (0.44) | PPARGACHEAGTR1 | |
| SCHEMBL9308844 | 0.85 | PPARG (0.45) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9846018 | 0.84 | ACHE (0.44) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9308512 | 0.84 | PPARG (0.45) | PPARGACHEAGTR1ALDH1A1HPGD | |
| SCHEMBL9308516 | 0.83 | PPARG (0.44) | PPARGACHEAGTR1ALDH1A1HPGD | |
| SCHEMBL9846045 | 0.83 | ACHE (0.43) | PPARGACHEAGTR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |
| US-5217973-A | Treatment of cardiovascular diseases such as hypertension, cardiac insufficiency and diseases of the arterial walls | LABORATOIRES UPSA (FR) | 1993-06-08 | — | — | US | disclosed |