Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309290 | 0.87 | PPARG (0.46) | ACHEPPARGAGTR1AGTR2 | |
| SCHEMBL9846006 | 0.86 | PPARG (0.42) | ACHEPPARGAGTR1AGTR2 | |
| SCHEMBL9846031 | 0.86 | PPARG (0.43) | ACHEPPARGHPGDAGTR1 | |
| SCHEMBL9308844 | 0.86 | PPARG (0.45) | ACHEPPARGAGTR1AGTR2 | |
| SCHEMBL9846018 | 0.85 | ACHE (0.44) | ACHEPPARGAGTR1AGTR2 | |
| SCHEMBL9846004 | 0.84 | PPARG (0.44) | ACHEPPARGAGTR1 | |
| SCHEMBL9846082 | 0.83 | ACHE (0.42) | ACHEPPARGAGTR1AGTR2 | |
| SCHEMBL9308911 | 0.83 | PPARG (0.41) | ACHEPPARGALDH1A1HPGDAGTR1 | |
| SCHEMBL9846003 | 0.82 | PPARG (0.40) | ACHEPPARGAGTR1AGTR2 | |
| SCHEMBL14245333 | 0.81 | PPARG (0.39) | ACHEPPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |