Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25962960 | 0.96 | SIGMAR1 (0.68) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL11934948 | 0.87 | SIGMAR1 (0.53) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL2910424 | 0.87 | TAAR1 (0.59) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL18551667 | 0.85 | L3MBTL1 (0.67) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL18326926 | 0.85 | S1PR2 (0.58) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL10567971 | 0.84 | ALDH1A1 (0.70) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8508426 | 0.82 | ESR1 (0.74) | S1PR1S1PR3S1PR4ESR1ADRA2A | |
| SCHEMBL10863129 | 0.82 | ESR1 (0.74) | S1PR1S1PR3S1PR4ESR1ADRA2A | |
| SCHEMBL6682161 | 0.82 | ESR1 (0.74) | S1PR1S1PR3S1PR4ESR1ADRA2A | |
| SCHEMBL5426427 | 0.82 | ESR1 (0.74) | S1PR1S1PR3S1PR4ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424965-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |
| US-4960934-A | Amine oxide process | ETHYL CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4942260-A | REACTION OF A TERT-AMINE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF CATALYTIC CARBON DIOXIDE | ETHYL CORPORATION (US) | 1990-07-17 | — | — | US | disclosed |
| EP-0356918-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0307184-A2 | Preparation of Amine Oxides | ETHYL CORPORATION (US) | 1989-03-15 | — | — | EP | disclosed |