Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279553 | 0.93 | KCNH2 (0.51) | KCNH2SIGMAR1LMNAHTR2AHRH1 | |
| SCHEMBL28279550 | 0.88 | LMNA (0.43) | KCNH2SIGMAR1LMNATDP1HTR2A | |
| SCHEMBL27916857 | 0.87 | SIGMAR1 (0.44) | KCNH2MEN1KMT2ANPSR1SIGMAR1 | |
| SCHEMBL9846066 | 0.85 | SIGMAR1 (0.47) | KCNH2MEN1KMT2ANPSR1SIGMAR1 | |
| Hexane SCHEMBL28249674 | 0.83 | KCNH2 (0.45) | KCNH2MEN1KMT2ASIGMAR1LMNA | |
| SCHEMBL2530767 | 0.80 | SIGMAR1 (0.50) | KCNH2SIGMAR1HTR2AHRH1DRD2 | |
| SCHEMBL9990265 | 0.80 | MEN1 (0.44) | KCNH2MEN1KMT2ANPSR1SIGMAR1 | |
| SCHEMBL2595023 | 0.79 | LMNA (0.46) | KCNH2MEN1KMT2ASIGMAR1LMNA | |
| Water SCHEMBL29140161 | 0.78 | MEN1 (0.43) | KCNH2MEN1KMT2ANPSR1SIGMAR1 | |
| Bromide SCHEMBL6625831 | 0.78 | MEN1 (0.45) | KCNH2MEN1KMT2ASIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102533392-A | Working fluid composition for refrigerator machine and refrigerating machine oil | JX NIPPON OIL & ENERGY CORP | 2012-07-04 | — | — | CN | disclosed |
| CN-102482611-A | Refrigerator oil and working fluid composition for refrigerator | JX NIPPON OIL & ENERGY CORP | 2012-05-30 | — | — | CN | disclosed |