Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494818 | 0.86 | HTR2A (0.69) | HTR2AHRH1TAAR1RIPK1SLC6A4 | |
| SCHEMBL19905186 | 0.86 | HTR2A (0.69) | HTR2AHRH1TAAR1RIPK1SLC6A4 | |
| SCHEMBL2471404 | 0.86 | HTR2A (0.69) | HTR2AHRH1TAAR1RIPK1SLC6A4 | |
| SCHEMBL12158260 | 0.83 | RIPK1 (0.47) | HTR2AHRH1TAAR1SIGMAR1RIPK1 | |
| SCHEMBL9876791 | 0.79 | ALDH1A1 (0.51) | RIPK1KMT2ACASRCYP2D6CYP2C19 | |
| SCHEMBL598533 | 0.78 | RIPK1 (0.53) | HTR2ATAAR1SIGMAR1RIPK1AOC3 | |
| SCHEMBL28113806 | 0.78 | HTR2A (1.00) | HTR2AHRH1L3MBTL1SIGMAR1SLC6A4 | |
| SCHEMBL27577135 | 0.78 | RIPK1 (0.53) | TAAR1SIGMAR1RIPK1AOC3TRPA1 | |
| SCHEMBL7351847 | 0.77 | AOC3 (0.60) | HTR2AHRH1TAAR1RIPK1SLC6A4 | |
| SCHEMBL5543402 | 0.77 | HTR2A (0.44) | HTR2AHRH1TAAR1SIGMAR1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424965-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |
| US-4960934-A | Amine oxide process | ETHYL CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4942260-A | REACTION OF A TERT-AMINE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF CATALYTIC CARBON DIOXIDE | ETHYL CORPORATION (US) | 1990-07-17 | — | — | US | disclosed |
| EP-0356918-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4889954-A | DIALKYLCARBONATE CATALYST | ETHYL CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0307184-A2 | Preparation of Amine Oxides | ETHYL CORPORATION (US) | 1989-03-15 | — | — | EP | disclosed |