Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426449 | 0.88 | MTNR1A (0.56) | ALDH1A1HPGDMTNR1AMTNR1BEPHX2 | |
| SCHEMBL7487803 | 0.83 | NAAA (0.50) | NAAAMTNR1AMTNR1BEPHX2CNR1 | |
| SCHEMBL10324528 | 0.80 | NAAA (0.44) | NAAAMTNR1AMTNR1BEPHX2CNR1 | |
| SCHEMBL8024421 | 0.79 | RIPK1 (0.46) | ALDH1A1HPGDRIPK1POLB | |
| SCHEMBL9846075 | 0.79 | HTR2A (0.63) | ALDH1A1CASRKMT2ACYP2D6CYP2C19 | |
| SCHEMBL31505725 | 0.79 | HTR2A (0.58) | MTNR1AMTNR1BEPHX2CASRCNR1 | |
| SCHEMBL8024424 | 0.77 | TBXAS1 (0.53) | ALDH1A1CYP2D6CYP2C19RIPK1HDAC7 | |
| SCHEMBL12158260 | 0.77 | RIPK1 (0.47) | ALDH1A1CASRKMT2ACYP2D6CYP2C19 | |
| SCHEMBL6893009 | 0.77 | BCAT2 (0.51) | NAAAMTNR1AMTNR1BEPHX2CNR1 | |
| SCHEMBL3141390 | 0.77 | BCAT2 (0.51) | NAAAMTNR1AMTNR1BEPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |