Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846217 | 0.84 | PDE3B (0.37) | KDM4EMAPK1 | |
| SCHEMBL9432009 | 0.77 | CD274 (0.38) | TAAR1GAAKDM4E | |
| SCHEMBL9272505 | 0.77 | PDE4A (0.40) | GAAKDM4E | |
| SCHEMBL9431791 | 0.75 | MAPT (0.40) | KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL22595837 | 0.74 | POLB (0.35) | GAA | |
| SCHEMBL9432058 | 0.74 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL9846426 | 0.74 | PDE4A (0.35) | L3MBTL1 | |
| SCHEMBL9846391 | 0.73 | MAPT (0.34) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL9846287 | 0.71 | GAA (0.33) | TAAR1GAAL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9432036 | 0.71 | GAA (0.36) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |