Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846244 | 0.82 | APOBEC3A (0.30) | — | |
| SCHEMBL9846426 | 0.81 | PDE4A (0.35) | MAPTTSHRNPY1RNPY2RRAB9A | |
| SCHEMBL9846120 | 0.80 | PPARD (0.33) | PPARDTSHR | |
| SCHEMBL9846157 | 0.78 | ALDH1A1 (0.32) | MAPTPPARDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL9431791 | 0.76 | MAPT (0.40) | MAPTTSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9846220 | 0.75 | ALOX5 (0.32) | — | |
| SCHEMBL9846323 | 0.74 | — | — | |
| SCHEMBL9846324 | 0.74 | — | — | |
| SCHEMBL9846113 | 0.73 | P2RX3 (0.34) | SMN1; SMN2L3MBTL1 | |
| L-697661 SCHEMBL30432096 | 0.68 | CD38 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |