Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595837 | 0.81 | POLB (0.35) | GAAAPOBEC3AAPOBEC3GGRM1CRHR1 | |
| SCHEMBL5701682 | 0.78 | PIK3CA (0.40) | GAAAPOBEC3AAPOBEC3GGRM1TAAR1 | |
| SCHEMBL9432036 | 0.78 | GAA (0.36) | GAAAPOBEC3AAPOBEC3GGRM1POLB | |
| SCHEMBL9432009 | 0.76 | CD274 (0.38) | GAAAPOBEC3AAPOBEC3GGRM1TAAR1 | |
| SCHEMBL9272505 | 0.76 | PDE4A (0.40) | GAAGRM1POLB | |
| SCHEMBL9267418 | 0.75 | ALDH1A1 (0.39) | GAAAPOBEC3AAPOBEC3GGRM1L3MBTL1 | |
| SCHEMBL9262255 | 0.74 | GAA (0.57) | GAAMAPK1SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL9432058 | 0.74 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL9058235 | 0.73 | MAPT (0.38) | GAAGRM1SMN1; SMN2POLB | |
| SCHEMBL9266046 | 0.73 | GAA (0.52) | GAASMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |