Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 8/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846039 | 0.80 | PPARG (0.45) | APLNR | |
| SCHEMBL9846061 | 0.79 | AGTR1 (0.35) | — | |
| SCHEMBL9845994 | 0.78 | CYP19A1 (0.42) | APLNRCTSSCTSK | |
| SCHEMBL9846024 | 0.78 | PPARG (0.47) | APLNR | |
| SCHEMBL9846092 | 0.76 | PPARG (0.45) | APLNR | |
| SCHEMBL9846038 | 0.73 | PPARG (0.41) | APLNR | |
| SCHEMBL9846015 | 0.72 | PPARG (0.45) | APLNR | |
| SCHEMBL11753901 | 0.72 | TSHR (0.69) | CNR1CNR2CTSSCTSKMMP12 | |
| SCHEMBL9311025 | 0.72 | PPARG (0.49) | APLNR | |
| SCHEMBL14672161 | 0.70 | MMP12 (0.56) | CTSSCTSKMMP12MMP13HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424317-A2 | Pyrimidines | CIBA-GEIGY AG (CH) | 1991-04-24 | — | — | EP | disclosed |