Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846244 | 0.81 | APOBEC3A (0.30) | APOBEC3AAPOBEC3G | |
| SCHEMBL9846391 | 0.80 | MAPT (0.34) | PPARDTSHR | |
| SCHEMBL9278617 | 0.77 | MAPT (0.34) | HPGDTSHR | |
| SCHEMBL9846220 | 0.74 | ALOX5 (0.32) | HPGD | |
| SCHEMBL9846324 | 0.73 | — | — | |
| SCHEMBL9846323 | 0.73 | — | — | |
| SCHEMBL9432051 | 0.68 | APOBEC3A (0.33) | APOBEC3AAPOBEC3G | |
| L-697661 SCHEMBL30432096 | 0.67 | CD38 (0.31) | — | |
| SCHEMBL9846106 | 0.67 | PDE4A (0.34) | — | |
| SCHEMBL9846187 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |