Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846133 | 0.86 | PIK3CD (0.42) | PIK3CDPIK3CBDAGLAHCAR2TNKS | |
| SCHEMBL9680867 | 0.85 | MEN1 (0.36) | PIK3CDPIK3CBHCAR2TNKSPARP1 | |
| SCHEMBL9449230 | 0.83 | MAPT (0.50) | PIK3CDPIK3CBHCAR2APLNRMEN1 | |
| SCHEMBL9601892 | 0.77 | ALDH1A1 (0.36) | HCAR2APLNRALDH1A1MEN1HPGD | |
| SCHEMBL9278111 | 0.75 | PIK3CD (0.44) | PIK3CDPIK3CBPARP1ALDH1A1MEN1 | |
| SCHEMBL9846224 | 0.73 | PARP1 (0.37) | PIK3CDPIK3CBTNKSPARP1TNKS2 | |
| SCHEMBL9846095 | 0.72 | MAPT (0.50) | PIK3CDPIK3CBAPLNRMEN1KMT2A | |
| SCHEMBL9280614 | 0.71 | PIK3CD (0.42) | PIK3CDPIK3CBPARP1ALDH1A1MEN1 | |
| SCHEMBL9846101 | 0.70 | ALDH1A1 (0.38) | HCAR2TNKSPARP1TNKS2ALDH1A1 | |
| SCHEMBL9846186 | 0.70 | MAPT (0.48) | PIK3CDPIK3CBHCAR2APLNRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |