Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042880 | 0.80 | PIK3CD (0.43) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2792576 | 0.80 | ACHE (0.39) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9680689 | 0.80 | PIK3CD (0.43) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11514781 | 0.80 | PSMB8 (0.37) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL101890 | 0.78 | MAPT (0.39) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL23932494 | 0.77 | HRH4 (0.36) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL30041966 | 0.77 | HRH4 (0.36) | MAPTALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10464540 | 0.77 | RXRA (0.41) | MAPTKDM4ENPC1RAB9ACYP3A4 | |
| SCHEMBL16674770 | 0.77 | NR4A2 (0.37) | MAPTALDH1A1KDM4ECYP3A4TSHR | |
| SCHEMBL3954797 | 0.76 | PSMB8 (0.37) | MAPTALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |