SCHEMBL9680689

SCHEMBL9680689

Fc1cccc2oc(CCl)nc12

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.43
PIK3CB P42338 1/20 0.43
DAGLA Q9Y4D2 1/20 0.40
ALDH1A1 P00352 4/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 3/20 0.37
HSF1 Q00613 1/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
LMNA P02545 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 2/20 0.32
MEN1 O00255 1/20 0.32
PRNP P04156 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
F2 P00734 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2792619 0.82 PIK3CD (0.43) PIK3CDPIK3CBDAGLAALDH1A1MAPT
SCHEMBL9846141 0.80 MAPT (0.38) ALDH1A1MAPTKDM4ENPC1RAB9A
SCHEMBL23932494 0.79 HRH4 (0.36) ALDH1A1MAPTKDM4ENPC1RAB9A
SCHEMBL30041966 0.79 HRH4 (0.36) ALDH1A1MAPTKDM4ENPC1RAB9A
SCHEMBL2792576 0.79 ACHE (0.39) ALDH1A1MAPTKDM4ENPC1RAB9A
SCHEMBL22042880 0.79 PIK3CD (0.43) PIK3CDPIK3CBALDH1A1MAPTKDM4E
SCHEMBL11199245 0.77 DAGLA (0.48) PIK3CDPIK3CBDAGLAALDH1A1KDM4E
SCHEMBL103151 0.76 PIK3CD (0.39) PIK3CDPIK3CBDAGLAALDH1A1MAPT
SCHEMBL3656157 0.76 DAGLA (0.40) PIK3CDPIK3CBDAGLAALDH1A1MAPT
SCHEMBL24029488 0.75 GABRP (0.36) ALDH1A1MAPTKDM4ERAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed
EP-0481802-A1 Hydroxylated inhibitors of HIV reverse transcriptase MERCK & CO. INC. (US) 1992-04-22 EP disclosed
EP-0462800-A2 Inhibitors of HIV reverse transcriptase MERCK & CO. INC. (US) 1991-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 PIK3CD 3553/4885PIK3CB 3338/4885DAGLA 4182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.