SCHEMBL9846151

SCHEMBL9846151

CCc1cnccc1C(C)=NO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 5/20 0.37
KDM6B O15054 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2E1 P05181 1/20 0.35
CYP2C8 P10632 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2A6 P11509 1/20 0.35
CYP2B6 P20813 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4A O75164 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
KDM4D Q6B0I6 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236770 0.79 KDM4C (0.44) KDM4CKDM6BMEN1KMT2ACYP2E1
SCHEMBL115648 0.76 KDM4C (0.56) KDM4CKDM6BMEN1KMT2AKDM4E
SCHEMBL30100781 0.76 KDM4C (0.56) KDM4CKDM6BMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL1026385 0.74 KDM4C (0.54) KDM4CKDM6BMEN1KMT2AKDM4E
SCHEMBL1023958 0.74 KDM4C (0.42) KDM4CKDM6BMEN1KMT2ACYP2E1
SCHEMBL8594489 0.74 TDP1 (0.56) KDM4CKDM6BMEN1KMT2ACYP2E1
SCHEMBL1026384 0.74 KDM4C (0.42) KDM4CKDM6BMEN1KMT2ACYP2E1
SCHEMBL8459305 0.73 GABRA1 (0.41) MEN1KMT2ACYP2D6CYP2C19HTT
SCHEMBL29101876 0.73 GABRA1 (0.41) MEN1KMT2ACYP2D6CYP2C19HTT
SCHEMBL30990565 0.73 CYP2A6 (0.44) KDM4CKDM6BMEN1KMT2ACYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424538-A1 PYRIDINE DERIVATIVES AND THEIR SALTS, AND INSECTICIDAL/ACARICIDAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-05-02 EP disclosed