Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846178 | 0.85 | ALDH1A1 (0.31) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL9442179 | 0.82 | ELANE (0.36) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL9283877 | 0.79 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL6367001 | 0.76 | KMT2A (0.35) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL29456981 | 0.76 | KMT2A (0.35) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL9681873 | 0.70 | HCAR2 (0.34) | KMT2AMEN1KDM4ETSHRELANE | |
| SCHEMBL8532577 | 0.67 | TYMS (0.30) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9278111 | 0.66 | PIK3CD (0.44) | KMT2AMEN1ALDH1A1HPGDRAB9A | |
| SCHEMBL9681878 | 0.65 | KMT2A (0.35) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL9846168 | 0.65 | KMT2A (0.33) | KMT2AMEN1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |