Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846168 | 0.90 | KMT2A (0.33) | KMT2AMEN1KDM4ELMNAPOLB | |
| SCHEMBL6367001 | 0.87 | KMT2A (0.35) | KMT2AMEN1KDM4ELMNAPOLB | |
| SCHEMBL29456981 | 0.87 | KMT2A (0.35) | KMT2AMEN1KDM4ELMNAPOLB | |
| SCHEMBL9455992 | 0.84 | HCAR2 (0.33) | KMT2AMEN1HCAR2ALDH1A1HPGD | |
| SCHEMBL9682726 | 0.78 | RAB9A (0.39) | KMT2AMEN1KDM4ELMNAHCAR2 | |
| SCHEMBL9681377 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL9846309 | 0.77 | FABP4 (0.31) | KMT2AMEN1HCAR2ALDH1A1HPGD | |
| SCHEMBL9846072 | 0.74 | TYMS (0.32) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9681873 | 0.74 | HCAR2 (0.34) | KMT2AMEN1KDM4ELMNAPOLB | |
| L-697661 SCHEMBL599639 | 0.72 | FABP4 (0.34) | KMT2AMEN1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169769-A | Aerobic culture product | MERCK & CO., INC. (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |