Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846225 | 0.85 | KMT2A (0.32) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL8532577 | 0.83 | TYMS (0.30) | ALDH1A1MAPT | |
| SCHEMBL9280809 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MEN1HPGDKMT2APARP1 | |
| L-697661 SCHEMBL29456987 | 0.77 | FABP4 (0.34) | ALDH1A1MEN1HPGDKMT2AGLA | |
| L-697661 SCHEMBL599639 | 0.77 | FABP4 (0.34) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9278617 | 0.77 | MAPT (0.34) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9846157 | 0.77 | ALDH1A1 (0.32) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9846185 | 0.77 | ALDH1A1 (0.31) | ALDH1A1MEN1HPGDKMT2AGLA | |
| SCHEMBL9846155 | 0.76 | MEN1 (0.31) | ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL9283236 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MEN1HPGDKMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | claimed |
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |