Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 10/20 | 0.37 |
| ▸ | ATP4B | P51164 | 10/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846253 | 1.00 | L3MBTL1 (0.40) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9846147 | 0.88 | MEN1 (0.41) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9846142 | 0.88 | MEN1 (0.41) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9336639 | 0.83 | L3MBTL1 (0.43) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9338293 | 0.83 | L3MBTL1 (0.43) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9585229 | 0.83 | L3MBTL1 (0.40) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9585232 | 0.83 | L3MBTL1 (0.40) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9846231 | 0.82 | L3MBTL1 (0.41) | L3MBTL1ATP4AATP4BSTAT3HTT | |
| SCHEMBL9846237 | 0.82 | L3MBTL1 (0.41) | L3MBTL1ATP4AATP4BSTAT3HTT | |
| SCHEMBL9846140 | 0.81 | L3MBTL1 (0.40) | L3MBTL1ATP4AATP4BSTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |