Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262255 | 0.87 | GAA (0.57) | GAAKDM4ESMN1; SMN2POLBCYP1A2 | |
| SCHEMBL1741630 | 0.78 | GAA (0.50) | GAAKDM4ESMN1; SMN2POLBCYP1A2 | |
| SCHEMBL9846221 | 0.78 | CYP1A2 (0.49) | GAAKDM4ESMN1; SMN2POLBCYP1A2 | |
| SCHEMBL15174914 | 0.73 | GAA (0.60) | GAAKDM4ESMN1; SMN2POLBCYP1A2 | |
| SCHEMBL9846251 | 0.72 | GRM1 (0.37) | GAAKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL21705945 | 0.70 | GAA (0.36) | GAAKDM4EKDM5AALDH1A1HPGD | |
| SCHEMBL9846110 | 0.69 | GAA (0.55) | GAAKDM4ESMN1; SMN2POLBCYP1A2 | |
| SCHEMBL9846326 | 0.69 | GAA (0.76) | GAAKDM4ESMN1; SMN2POLBCYP1A2 | |
| SCHEMBL8594445 | 0.69 | GRM1 (0.37) | GAAKDM4ESMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9524583 | 0.68 | KDM4E (0.55) | GAAKDM4ESMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |