Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586720 | 0.77 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL15174914 | 0.77 | GAA (0.60) | GAALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL12772520 | 0.75 | ALDH1A1 (0.36) | GAALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12841773 | 0.75 | L3MBTL1 (0.38) | GAALMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9846326 | 0.72 | GAA (0.76) | GAALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9846214 | 0.72 | ERN1 (0.35) | GAAKDM4EALDH1A1 | |
| SCHEMBL9262255 | 0.71 | GAA (0.57) | GAALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL25842241 | 0.70 | GAA (0.46) | GAALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9846336 | 0.69 | GAA (0.51) | GAALMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL16044043 | 0.67 | GAA (0.49) | GAALMNASMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |