Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701789 | 0.79 | PEPD (0.48) | KDM4EALDH1A1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL1983930 | 0.77 | NPC1 (0.50) | KDM4EALDH1A1SIGMAR1ADRA2AADRA2B | |
| SCHEMBL11236640 | 0.77 | GRIN2D (0.58) | KDM4EALDH1A1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL1983932 | 0.77 | NPC1 (0.50) | KDM4EALDH1A1SIGMAR1ADRA2AADRA2B | |
| SCHEMBL10112792 | 0.77 | SIGMAR1 (0.58) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11232538 | 0.77 | GRIN2D (0.55) | KDM4EALDH1A1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL15094415 | 0.77 | GRIN2D (0.55) | KDM4EALDH1A1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL15366862 | 0.74 | MDM2 (0.44) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL160935 | 0.74 | MDM2 (0.44) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL11227305 | 0.73 | CRHBP (0.51) | ALDH1A1SIGMAR1POLBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456093-A2 | Biguanide derivatives and biocidal compositions containing them | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1991-11-13 | — | — | EP | disclosed |