Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632795 | 0.76 | KDM1A (0.39) | OPRM1OPRL1 | |
| SCHEMBL9632050 | 0.71 | — | — | |
| SCHEMBL9633035 | 0.70 | CYP1A2 (0.39) | SLC6A2CHRM3KMT2ASLC6A4 | |
| SCHEMBL9631894 | 0.68 | SLC6A3 (0.37) | SLC6A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9631898 | 0.68 | SLC6A3 (0.37) | SLC6A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9632881 | 0.68 | SLC6A3 (0.37) | SLC6A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9633105 | 0.68 | SLC6A2 (0.40) | SLC6A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9631477 | 0.67 | — | — | |
| SCHEMBL1837477 | 0.67 | HSD11B1 (0.44) | SLC6A2KMT2A | |
| SCHEMBL9633419 | 0.67 | OPRM1 (0.40) | SLC6A2CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432817-A1 | Diazirine derivatives of aromatic heterocyclic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-06-19 | — | — | EP | disclosed |