Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211075 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP3A4NPC1MAPTNPSR1 | |
| SCHEMBL11307252 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4NPC1MAPTGAA | |
| SCHEMBL10621551 | 0.82 | ACHE (0.43) | ALDH1A1CYP3A4NPC1MAPTNPSR1 | |
| SCHEMBL12209730 | 0.77 | CYP3A4 (0.42) | ALDH1A1CYP3A4NPC1MAPTGAA | |
| SCHEMBL29217792 | 0.75 | NPC1 (0.48) | ALDH1A1CYP3A4NPC1MAPTNPSR1 | |
| SCHEMBL30594536 | 0.74 | ACHE (0.44) | ALDH1A1CYP3A4NPC1MAPTGAA | |
| SCHEMBL8465680 | 0.74 | ACHE (0.50) | ALDH1A1CYP3A4NPC1MAPTGAA | |
| SCHEMBL26113643 | 0.74 | ACHE (0.44) | ALDH1A1CYP3A4NPC1MAPTGAA | |
| SCHEMBL926329 | 0.73 | L3MBTL1 (0.67) | ALDH1A1CYP3A4NPC1MAPTGAA | |
| SCHEMBL29532421 | 0.73 | NPC1 (0.56) | ALDH1A1CYP3A4NPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |
| EP-0416962-A1 | Keratinous fibers dyeing process with indole dyes and oxidation dye precursors and dyeing agents | L'OREAL (FR) | 1991-03-13 | — | — | EP | disclosed |