Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947358 | 0.81 | HSD17B10 (0.47) | HSD17B10MAOAMAOBSCN9ANPC1 | |
| SCHEMBL6482247 | 0.79 | L3MBTL1 (0.49) | HSD17B10MAOAMAOBSCN9ANPC1 | |
| SCHEMBL29497647 | 0.78 | RAB9A (0.48) | SCN9ANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL23195821 | 0.77 | POLB (0.46) | HSD17B10SCN9ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21773120 | 0.76 | HSD17B10 (0.42) | HSD17B10MAOAMAOBSCN9ANPC1 | |
| SCHEMBL38664086 | 0.76 | RAB9A (0.45) | HSD17B10MAOAMAOBSCN9ANPC1 | |
| SCHEMBL31468117 | 0.76 | SCN9A (0.51) | HSD17B10MAOAMAOBSCN9ANPC1 | |
| SCHEMBL16011599 | 0.74 | L3MBTL1 (0.50) | HSD17B10NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL20609867 | 0.74 | HSD17B10 (0.47) | HSD17B10NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL2887792 | 0.74 | SCN9A (0.52) | HSD17B10MAOAMAOBSCN9ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457581-A1 | Herbicidal sulfonylurea derivatives | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1991-11-21 | — | — | EP | disclosed |