Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23261408 | 0.65 | GAA (0.38) | EGFRMAPK1SMN1; SMN2CFTRGOPC | |
| SCHEMBL576517 | 0.63 | SMN1; SMN2 (0.40) | MAPK1SMN1; SMN2CFTRGOPCESR1 | |
| SCHEMBL11469864 | 0.62 | CFTR (0.39) | MAPK1SMN1; SMN2CFTRGOPCALDH1A1 | |
| SCHEMBL17694647 | 0.62 | SMN1; SMN2 (0.39) | MAPK1SMN1; SMN2CFTRGOPCESR1 | |
| SCHEMBL9846586 | 0.60 | EGFR (0.40) | EGFRMAPK1SMN1; SMN2CFTRGOPC | |
| SCHEMBL23214499 | 0.60 | HCAR2 (0.45) | EGFRCFTRGOPCALDH1A1 | |
| SCHEMBL7635908 | 0.59 | CFTR (0.56) | EGFRMAPK1SMN1; SMN2CFTRGOPC | |
| SCHEMBL20251141 | 0.59 | MAPK1 (0.40) | MAPK1SMN1; SMN2CFTRGOPCALDH1A1 | |
| SCHEMBL29531709 | 0.59 | CRHBP (0.41) | SMN1; SMN2ESR1ESR2ALDH1A1 | |
| SCHEMBL9846576 | 0.58 | EGFR (0.32) | EGFRSMN1; SMN2CFTRGOPCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455909-A2 | 5-[1-(Imidazol)methyl]-3,3-disubstituted-2(3H) furanone derivatives | MARION MERRELL DOW INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5039691-A | Anticholinergic agents | MARION MERRELL DOW INC. (US) | 1991-08-13 | — | — | US | disclosed |