Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772859 | 0.82 | GAA (0.37) | EGFRTSHRCFTRGOPCGAA | |
| SCHEMBL7674692 | 0.82 | MAOB (0.33) | EGFRBACE1BACE2RENAPP | |
| SCHEMBL4394813 | 0.76 | SLC6A2 (0.34) | TSHRBACE1BACE2GAASMN1; SMN2 | |
| SCHEMBL9772838 | 0.73 | — | — | |
| SCHEMBL9846603 | 0.72 | MMP2 (0.34) | ALDH1A1BACE1BACE2RENAPP | |
| SCHEMBL4395561 | 0.71 | CYP11B1 (0.49) | MAPT | |
| SCHEMBL11469864 | 0.61 | CFTR (0.39) | ALDH1A1BACE1BACE2CFTRGOPC | |
| SCHEMBL4397735 | 0.59 | CFTR (0.34) | ALDH1A1BACE1BACE2RENAPP | |
| SCHEMBL9846594 | 0.58 | EGFR (0.33) | EGFRALDH1A1CFTRGOPCSMN1; SMN2 | |
| SCHEMBL7635908 | 0.58 | CFTR (0.56) | EGFRALDH1A1TSHRCFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455909-A2 | 5-[1-(Imidazol)methyl]-3,3-disubstituted-2(3H) furanone derivatives | MARION MERRELL DOW INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5039691-A | Anticholinergic agents | MARION MERRELL DOW INC. (US) | 1991-08-13 | — | — | US | disclosed |