Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9846785 | 0.85 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9846680 | 0.72 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL988193 | 0.72 | SLC6A4 (0.53) | LMNATP53MAPT | |
| SCHEMBL9846700 | 0.70 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL10576800 | 0.68 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9846761 | 0.67 | AGTR1 (0.45) | TLR8AGTR1AGTR2 | |
| SCHEMBL9309540 | 0.66 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9846708 | 0.66 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL27562946 | 0.66 | CYP1A2 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9309546 | 0.66 | AGTR1 (0.54) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |