Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846728 | 0.85 | AGTR1 (0.67) | AGTR1AGTR2PPARGFFAR1 | |
| SCHEMBL9846714 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2PPARGFFAR1MAPT | |
| SCHEMBL9846708 | 0.83 | AGTR1 (0.54) | AGTR1AGTR2PPARGFFAR1HSP90AA1 | |
| SCHEMBL9846705 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL29136624 | 0.71 | AGTR1 (0.57) | AGTR1AGTR2KCNH2HSP90AA1 | |
| SCHEMBL9214231 | 0.71 | AGTR1 (0.66) | AGTR1AGTR2KCNH2HDAC1HPGD | |
| SCHEMBL9846692 | 0.70 | AGTR1 (0.43) | AGTR1AGTR2HSP90AA1 | |
| SCHEMBL29037510 | 0.69 | AGTR1 (0.57) | AGTR1AGTR2KCNH2HDAC1HSP90AA1 | |
| SCHEMBL9846721 | 0.69 | AGTR1 (0.64) | AGTR1AGTR2HDAC1 | |
| SCHEMBL11014930 | 0.68 | AGTR1 (0.61) | AGTR1AGTR2KCNH2HDAC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |