Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776590 | 0.80 | ACHE (0.48) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL16804123 | 0.78 | ACHE (0.46) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL497622 | 0.76 | LMNA (0.46) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL21077473 | 0.76 | ACHE (0.44) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL9846739 | 0.75 | LTA4H (0.41) | TSHRCA1CA2CA9L3MBTL1 | |
| SCHEMBL3883731 | 0.74 | ACHE (0.48) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL3884014 | 0.73 | HTT (0.48) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL16625869 | 0.73 | ACHE (0.41) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL3887583 | 0.70 | ACHE (0.38) | ACHETSHRCYP3A4LMNACA1 | |
| SCHEMBL27579788 | 0.70 | CA1 (0.44) | ACHETSHRCYP3A4LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | claimed |
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |