Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846763 | 0.80 | NR1H2 (0.51) | NR1H2NR1H3BRD4CREBBP | |
| SCHEMBL8820122 | 0.80 | NR1H2 (0.62) | NR1H2NR1H3 | |
| SCHEMBL9846756 | 0.80 | NR1H2 (0.48) | NR1H2NR1H3BRD4CREBBPCA12 | |
| SCHEMBL16031735 | 0.79 | NR1H2 (0.43) | NR1H2NR1H3CA12CA9ATR | |
| SCHEMBL21657872 | 0.76 | NR1H2 (0.52) | NR1H2NR1H3BRD4CREBBPCA12 | |
| SCHEMBL10173695 | 0.74 | NR1H2 (0.49) | NR1H2NR1H3CA12CA9ATR | |
| SCHEMBL3001991 | 0.74 | NR1H2 (0.65) | NR1H2NR1H3 | |
| SCHEMBL16760212 | 0.72 | NR1H2 (0.52) | NR1H2NR1H3ATRATRIP | |
| SCHEMBL27983070 | 0.72 | NR1H2 (0.48) | NR1H2NR1H3ATRATRIP | |
| SCHEMBL17220643 | 0.72 | NR1H2 (0.74) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |