Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846675 | 0.80 | CCNB2 (0.42) | SLC6A3CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL9846745 | 0.76 | CCNB2 (0.44) | SLC6A3LMNACCNB2CDK1CCNB1 | |
| SCHEMBL2138912 | 0.70 | CHRM2 (0.41) | NR1H2 | |
| SCHEMBL5284224 | 0.69 | ALDH1A1 (0.55) | SLC6A3ALDH1A1LMNASLC6A4KCNA5 | |
| SCHEMBL10433539 | 0.68 | KCNA5 (0.47) | SLC6A3ALDH1A1LMNASLC6A4KCNA5 | |
| SCHEMBL9846683 | 0.68 | NR1H2 (0.43) | SLC6A3NR1H2SLC6A4BRD4MEN1 | |
| SCHEMBL1760164 | 0.68 | ALDH1A1 (0.53) | PTGDR2SLC6A3ALDH1A1LMNAKMT2A | |
| SCHEMBL21463865 | 0.68 | MEN1 (0.53) | PTGDR2ALDH1A1LMNANR1H2MEN1 | |
| SCHEMBL30285064 | 0.67 | KMT2A (0.46) | SLC6A3ALDH1A1LMNASLC6A4BRD4 | |
| SCHEMBL7170821 | 0.66 | ALDH1A1 (0.49) | SLC6A3ALDH1A1LMNASLC6A4KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |